Plasmonic elastic capsules as colorimetric reversible pH-microsensors

TL;DR

This paper introduces plasmonic elastic capsules combining gold nanoparticles and pH-responsive shells that reversibly change color with pH, offering a simple, reusable, and effective microsensor for detecting local pH variations and bacterial growth.

Contribution

The study presents a novel design of plasmonic capsules that are easy to produce, reversible, and capable of detecting pH changes through colorimetric shifts, addressing limitations of existing microsensors.

Findings

Capsules swell or shrink with pH changes, altering nanoparticle distances.

Color change is unambiguous and reversible over a large pH range.

Potential application demonstrated in detecting bacterial growth.

Abstract

There is a crucial need for effective and easily dispersible colloidal microsensors able to detect local pH changes before irreversible damages caused by demineralization, corrosion, or biofilms occur. One class of such microsensors is based on molecular dyes encapsulated or dispersed either in polymer matrices or in liquid systems exhibiting different colors upon pH variations. They are efficient but often rely on sophisticated and costly syntheses, and present significant risks of leakage and photobleaching damages, which is detrimental for mainstream applications. Another approach consists in exploiting the distance-dependent plasmonic properties of metallic nanoparticles. Still, assembling nanoparticles into dispersible colloidal pH-sensitive sensors remains a challenge. Here, we show how to combine optically active plasmonic gold nanoparticles and pH-responsive thin shells into "plasmocapsules". Upon pH change, plasmocapsules swell or shrink. Concomitantly, the distance between the gold nanoparticles embedded in the polymeric matrix varies, resulting in an unambiguous color change. Billions of micron-size sensors can thus be easily fabricated. They are non-intrusive, reusable, and sense local pH changes. Each plasmocapsule is an independent reversible microsensor over a large pH range. Finally, we demonstrate their potential use for the detection of bacterial growth, thus proving that plasmocapsules are a new class of sensing materials.