Long-lived state in a four-spin system hyperpolarized at room temperature

TL;DR

This paper demonstrates the creation of a long-lived hyperpolarized state in a four-spin system at room temperature, enabling chemical sensing without low-temperature hyperpolarization.

Contribution

It introduces a method to encode hyperpolarized nuclear spins into a long-lived state at room temperature, expanding practical applications in chemical sensing.

Findings

Successful encoding of a four-spin hyperpolarized state at room temperature.

Application of the long-lived state as a sensor in ligand-receptor experiments.

Potential for room-temperature hyperpolarization in chemical sensing.

Abstract

A solution with hyperpolarized nuclear spins encoded into a long-lived state has been utilized for sensing chemical phenomena. In a conventional way, nuclear spins are hyperpolarized at very low temperatures. In this work, we demonstrate the encoding of a four-nuclear-spin system hyperpolarized at room temperature into a long-lived state in a solution. We apply the solution with the long-lived state as a sensor in ligand--receptor binding experiments.