Nonparametric Shrinkage Estimation in High Dimensional Generalized Linear Models via Polya Trees
Asaf Weinstein, Jonas Wallin, Daniel Yekutieli, Ma{\l}gorzata Bogdan

TL;DR
This paper introduces a nonparametric Bayesian shrinkage estimator for high-dimensional generalized linear models, leveraging Polya trees to adaptively regularize coefficients and improve estimation accuracy over existing methods.
Contribution
It proposes a hierarchical Bayesian approach using Polya tree priors to nonparametrically estimate coefficient distributions, achieving universal optimality in regularization.
Findings
Outperforms parametric and nonparametric alternatives in estimation accuracy.
Adapts nonparametrically to the empirical distribution of true coefficients.
Demonstrates improved prediction in high-dimensional regression.
Abstract
Regularization in fitting regression models has been a highly active topic of research in the past few decades, but most of the existing methods are designed for particular situations, e.g. for the case of a sparse coefficient vector. We consider the problem of designing optimal regularized estimators in a given generalized linear model with fixed effects. First, we propose as a contender the Bayes estimator against an prior that assigns equal mass to every permutation of the fixed coefficient vector, thus depending on the true coefficients only through their empirical CDF. We prove some optimality properties of this oracle estimator in both the frequentist and Bayesian frameworks. To compete with the oracle estimator, we posit a hierarchical Bayes model where the individual coefficients are modeled as i.i.d. draws from a common distribution…
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Taxonomy
TopicsGene expression and cancer classification · Genetic Mapping and Diversity in Plants and Animals · Bayesian Methods and Mixture Models
