A simulation model for longitudinal HIV viral load and mother-to-child-transmission in pregnant and postpartum women
Maia Lesosky, Janet Raboud, Tracy Glass, Elaine Abrams, Landon Myer
TL;DR
This paper introduces VLSiM-PPW, a Monte Carlo simulation model designed to analyze HIV viral load dynamics and mother-to-child transmission risks during pregnancy and postpartum periods.
Contribution
It presents a detailed model specification for simulating HIV adherence, viral load, and transmission in pregnant and breastfeeding women, filling a gap in existing modeling approaches.
Findings
Model accurately simulates viral load trajectories.
Provides insights into transmission risk factors.
Supports intervention strategy evaluation.
Abstract
This manuscript describes the model specification, including input and output measures, dependencies, and structure for VLSiM-PPW, a Monte Carlo type model for HIV adherence, viral load and vertical transmission in pregnant and breastfeeding women.
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Taxonomy
TopicsHIV/AIDS Research and Interventions · HIV, Drug Use, Sexual Risk · Adolescent Sexual and Reproductive Health