# One-Way Coupled Tumor Response Model for Combined-Hyperthermia-Radiotherapy Treatment with Anisotropic Scattering

## TL;DR

This paper extends a tumor response model for combined hyperthermia and radiotherapy treatments by incorporating anisotropic scattering into the radiation transport component, improving the model's realism.

## Contribution

It introduces an extension of the previous isotropic scattering model to include anisotropic scattering in the radiation transport simulation.

## Key findings

- Enhanced accuracy in modeling radiation transport with anisotropic scattering
- Improved understanding of heat and radiation effects on tumor dynamics
- Foundation for more realistic treatment simulations

## Abstract

Therapies such as combined-hyperthermia-radiotherapy (CHR) take advantage of excellent radiosensitization properties of hyperthermia and treat of tumors with both radiation and heat. To appropriately model a CHR treatment, features like tumor heating (heat transfer), dosimetry (radiation transport), and tumor dynamics (cell population dynamics) must be considered together. Our first paper on modeling such treatments introduced a one-way coupled model that could only account for isotropic scattering of radiation. In the present work, we extend our transport model to incorporate anisotropic scattering.