Analysis of retinal and choroidal images measured by laser Doppler holography

TL;DR

This paper demonstrates that laser Doppler holography (LDH) can quantitatively differentiate arteries and veins in the retina and choroid by analyzing blood flow waveforms and frequency images, offering high temporal resolution non-invasive imaging.

Contribution

It introduces a method to distinguish retinal and choroidal arteries and veins using LDH's high temporal resolution and frequency-based analysis, advancing non-invasive ocular blood flow imaging.

Findings

Arteries and veins in the retina can be differentiated by their Doppler waveforms.

Choroidal arteries and veins are discriminated by low and high frequency power Doppler images.

LDH provides high temporal resolution blood flow measurements in the eye.

Abstract

Laser Doppler holography (LDH) is a full-field imaging technique that was recently used in the human eye to reveal blood flow contrasts in the retinal and choroidal vasculature non-invasively, and with high temporal resolution. We here demonstrate that the ability of LDH to perform quantitative flow measurements with high temporal resolution enables arteriovenous differentiation in the retina and choroid. In the retina, arteries and veins can be differentiated on the basis of their respective power Doppler waveforms. Choroidal arteries and veins can instead be discriminated by computing low and high frequency power Doppler images to reveal low and high blood flow images, respectively.