Structure of singularities in the nonlinear nerve conduction problem
Aram Karakhanyan

TL;DR
This paper characterizes the structure of singular points on the free boundary in a nonlinear nerve conduction model, revealing geometric properties and stratification near these points, especially in two dimensions.
Contribution
It provides a detailed analysis of the free boundary's singularities in a nonlinear PDE model of nerve impulses, including geometric descriptions and stratification methods.
Findings
Near flat singular points, the free boundary consists of four $C^1$ arcs in 2D.
In the linear case, the singular set decomposes into degenerate and flat points.
Blow-ups of solutions at certain points are homogeneous functions.
Abstract
We give a characterisation of the singular points of the free boundary for viscosity solutions of the nonlinear equation \begin{equation}F(D^2 u)=-\chi_{\{u>0\}},\tag{0.1} \end{equation} where is a fully nonlinear elliptic operator and the characteristic function. The equation (0.1) models the propagation of a nerve impulse along an axon. We analyse the structure of the free boundary near the singular points where and vanish simultaneously. Our method uses the stratification approach developed in [DK18]. In particular, when we show that near a rank-2 flat singular free boundary point is a union of four arcs tangential to a pair of crossing lines. Moreover, if is linear then the singular set of is the union of degenerate and rank-2 flat points. We also provide an…
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Taxonomy
TopicsNonlinear Partial Differential Equations · Advanced Mathematical Modeling in Engineering · Numerical methods in inverse problems
Structure of singularities in the nonlinear nerve conduction problem
Aram L. Karakhanyan
School of Mathematics, University of Edinburgh, Peter Guthrie Tait Road Edinburgh, EH9 3FD
[email protected] www.maths.ed.ac.uk/$\sim$aram
(Date: (Last Typeset))
Abstract.
We give a characterization of the singular points of the free boundary for viscosity solutions of the nonlinear equation
[TABLE]
where is a fully nonlinear elliptic operator and the characteristic function. The equation (0.1) models the propagation of a nerve impulse along an axon.
We analyze the structure of the free boundary near the singular points where and vanish simultaneously. Our method uses the stratification approach developed in [DK].
In particular, when we show that near a rank-2 flat singular free boundary point is a union of four arcs tangential to a pair of crossing lines. Moreover, if is linear then the singular set of is the union of degenerate and rank-2 flat points.
We also provide an application of the boundary Harnack principles to study the higher order flat degenerate points, and show that if is a cone then the blow-ups of are homogeneous functions.
Key words and phrases:
Free boundary regularity, fully nonlinear elliptic operator, nerve impulse propagation problem, obstacle problem
2010 Mathematics Subject Classification:
35R35.
1. Introduction
In this paper we study the free boundary problem
[TABLE]
where is a given bounded domain with boundary, the characteristic function function of , and a convex fully nonlinear elliptic operator satisfying some structural conditions. The partial differential equation (1.1) appears in a model of the nerve impulse propagation [Feroe], [Pauwelussen], [Rinzel].
It comes from the following linearized diffusion system of FitzHugh
[TABLE]
where is the voltage across the nerve membrane at distance and time , and components of model the conductance of the membrane to various ions [Feroe]. Mckean suggested to consider [McKean]. Due to the homogeneity of the equation the linear term disappears after quadratic scaling, so we neglect it.
The linearized steady state equation
[TABLE]
also arises in a solid combustion model [Monneau-W], and the composite membrane problem, see [Kenig], also [CK] for its variational formulation.
A chief difficulty is to analyze the free boundary near singular points where both and vanish. The main technique used in [Monneau-W], [Kenig], [CK] is a monotonicity formula, which is not available for the nonlinear equations. The aim of this paper is to use the boundary Harnack principles and anisotropic scalings to develop a new approach to circumvent the lack of the monotonicity formula and obtain some of the main results from [Monneau-W] and [Lee-Sh] for the fully nonlinear case. More precisely, in this paper we address the optimal regularity, degeneracy and the shape of the free boundary near the singular points.
One of the main results in [Monneau-W] concerns the cross shaped singularities in . It follows from the classification of homogeneous solutions and an application of the monotonicity formula introduced in [Monneau-W]. For nonlinear equations this method cannot be applied. We remark that the degenerate case (i.e. when near a free boundary point ) cannot be treated by the monotonicity formula introduced in [Monneau-W] because it does not provide any qualitative information about , see Proposition 5.1 [Monneau-W]. Another approach was recently used in [ST].
It is well known that the strong solutions of (1.3) may not be , see [Chemin] Proposition 5.3.1. However, if then is always log-Lipschitz continuous [Yudovich] Lemma 2.1. For general elliptic operators one can show that is for every , [CC-Fully], see also Remark 2.2 in Section 2.
Another approach, based on Harnack inequalities, had been developed by Tolksdorf to prove the existence of homogeneous solutions for in cones [Tolksdorf] . We employ this approach in Section 6.
The problem (1.3) has some resemblance with the classical obstacle problem [Caff-cpde]. For the fully nonlinear operators the obstacle problem has been studied in [Lee] for one phase and in [Xavier] for the thin obstacle.
The paper is organized as follows: In Section 2 we state some technical results. In Section 3 we prove the existence of viscosity solutions using a penalization argument. We also show the existence of a maximal solution and establish its non-degeneracy. Section 4 contains the proof of the following dichotomy: either the free boundary points are rank-2 flat or the solution has quadratic growth. As a consequence we show that if then near a rank-2 flat point the free boundary is a union of four curves tangential to a pair of crossing lines. This is done in Section 5. Finally, in Section 6 we use a boundary Harnack principle to prove the homogeneity of blow-ups near conical free boundary points.
2. Technical results
Throughout this paper denotes the open ball of radius centered at and . For continuous function we let , , , and is the singular subset of the free boundary , where .
We shall make two standing assumptions on the operators under consideration. To formulate them we let be the space of symmetric matrices and positive definite symmetric matrices with eigenvalues bounded between two positive constants and .
The operator is uniformly elliptic, i.e. there are two positive constants such that
[TABLE]
for every nonnegative matrix .
is smooth except the origin and homogeneous of degree one , and .
For smooth the hypothesis is equivalent to
[TABLE]
where .
Typically, , where is the index set and such that . Notice that if then .
We also define Pucci’s extremal operators
[TABLE]
where are the eigenvalues of .
Definition 2.1**.**
A continuous function is said to be a viscosity solution of , if the equation holds pointwise, whenever at the graph of can be touched from above and below by paraboloids .
Remark 2.2**.**
If is concave and is a viscosity solution of in then
[TABLE]
where and are universal constants, see Theorem 6.6 [CC-Fully]. If is convex or concave then for the viscosity solutions of we still have the estimate
[TABLE]
(see (6.14) and Remark 1 on page 60 in [CC-Fully]). Theorem 5.2 is the only place where we require to be convex.
Under assumptions the classical weak and strong comparison principles are valid for the viscosity solutions [CC-Fully]. Moreover, we have the strong and Hopf’s comparison principles.
Lemma 2.3** (Strong comparison principle).**
Suppose , and in a bounded domain . Let in in viscosity sense, , and are not identical, then
[TABLE]
See Theorem 3.1 [Giga].
Lemma 2.4** (Hopf’s comparison principle).**
Let be a ball contained in and assume that and that , in . Let and be a viscosity subsolution and a supersolution of , respectively. Moreover, suppose that , in , and that , for some . Then, .
See Theorem 4.1 [Giga].
One of the main tools in our analysis is the boundary Harnack principle. As before, we assume that is smooth, homogeneous of degree 1, uniformly elliptic with ellipticity constants and , and . We use the following notation: is Lipschitz continuous function with Lipschitz constant , , , .
Then we have the following Harnack principle, see [Wang].
Theorem 2.5**.**
Assume hold and is either concave or convex. Let be two nonnegative solution of in that equal 0 along . Suppose also that in for some . Then for some constant , depending only on and the Lipschitz character of , we have in
[TABLE]
Furthermore, as in [C-1] (see also [Wang] Section 2) one can show that the nonnegative solutions in are monotone in for some universal . We state this only in two spatial dimensions.
Theorem 2.6**.**
Let be a viscosity solution of in , . Assume hold and is either concave or convex. Then there is such that
[TABLE]
In [Wang] Theorem 2.6 is stated for concave operator , however the concavity is needed only to assure that locally the viscosity solutions of the homogeneous equation are locally regular, see Remark 1.2 in [Wang]. Since in the proofs of Lemmata 2.1-2.5 in [Wang] one needs only regularity of the solutions then in view of Remark 2.2 we see that Theorem 2.6 continues to hold for convex , see [Feldman].
Finally, we give a characterization of homogeneity, see Theorem 2.1.1 [Tolksdorf] for a proof.
Lemma 2.7**.**
Let where such that
[TABLE]
Then there is a such that
[TABLE]
3. Existence and nongeneracy
In this section we prove the existence of viscosity solutions and the non-degeneracy of maximal solutions.
3.1. Existence of viscosity solutions
Definition 3.1**.**
A continuous function is said to be a viscosity subsolution of , if the inequality holds pointwise, whenever at the graph of can be touched from below by a paraboloid . Moreover, is said to be a strict subsolution if the inequality above is strict.
Definition 3.2**.**
A viscosity solution of is said to be maximal in if for every strong subsolution satisfying on for some subdomain we have in .
Theorem 3.3**.**
Assume hold. Let be a bounded domain and . There exists a viscosity solution to
[TABLE]
such that for every .
Proof.
We use a standard penalization argument [Friedman]. Let be a family of functions such that
[TABLE]
Given , there is a solution of
[TABLE]
Observe that Perron’s method implies that for every the maximal solution exists. Furthermore, since are uniformly bounded then with some independent of , see Theorem 7.1 [CC-Fully] and Remark 2.2 above.
If is a subsolution, i.e. then by (3.2) we also have . Thus for (using (3.2)) we get
[TABLE]
This shows that is a subsolution to (3.3). Since is the maximal solution then we have
[TABLE]
Thus in . From the uniform convergence it follows that implying that in some neighborhood of . Thus near . Since a.e. on it follows that . ∎
3.2. Non-degeneracy
Theorem 3.4**.**
Assume hold. Let be the maximal solution, then there is a universal constant , depending only on dimension and , such that
[TABLE]
implies that .
Proof.
Let us consider
[TABLE]
where
[TABLE]
and the constant is chosen so that is regular. It is straightforward to compute and thus
[TABLE]
From the ellipticity (2.1) we get that
[TABLE]
Hence
[TABLE]
Consequently, we see that is a subsolution.
Given , choose so that . Then for we have
[TABLE]
and consequently
[TABLE]
Thus .
∎
4. Dichotomy
In order to formulate the main result of this section we first introduce the notion of rank-2 flatness. Let be the set of all homogeneous normalized polynomials of degree two, i.e.
[TABLE]
where is a symmetric matrix. For given and , we set and consider the zero level set of translated polynomial
[TABLE]
By definition is a cone with vertex at .
Definition 4.1**.**
Let , and . We say that is -rank-2 flat at if, for every , there exists such that
[TABLE]
Here denotes the Hausdorff distance defined as follows
[TABLE]
Given , and , we let
[TABLE]
Then, we define the rank-2 flatness at level of at as follows.
Definition 4.2**.**
Let , and . We say that is -rank-2 flat at level at if , where
[TABLE]
In view of Definitions 4.1 and 4.2, we can say that is -rank-2 flat at if and only if, for every , it is -rank-2 flat at level at .
Theorem 4.3**.**
Let and be a viscosity solution of (1.1). Let , and let such that and is not -rank-2 flat at at any level . Then, has at most quadratic growth at , bounded from above in dependence on .
Theorem 4.3 will follow from Proposition 4.4 below in standard way, see [DK]. Let us define and where .
Proposition 4.4**.**
Let be as in Theorem 4.3 and . If
[TABLE]
for some , then there exists such that
[TABLE]
Proof.
If (4.6) fails then there are solutions of (1.1) with , sequences of integers, and free boundary points such that
[TABLE]
where with some abuse of notation we set . Since it follows that . Define the scaled functions
[TABLE]
By construction we have
[TABLE]
where the last inequality follows from (4.7) after rescaling the inequality . Utilizing the homogeneity of operator and noting that
[TABLE]
it follows that
[TABLE]
where . Observe that in view of (4.7). Since under hypotheses we have local bounds for all (see Theorem 7.1 [CC-Fully]) it follows that we can employ a customary compactness argument for the viscosity solutions to show that there is a function such that
[TABLE]
From Liouville’s theorem it follows that is homogeneous quadratic polynomial of degree two. This is in contradiction with (4.9) and the proof is complete. ∎
Remark 4.5**.**
In [Lee-Sh] the authors proved some partial results for the problem
[TABLE]
For this problem arises in the linear potential theory related to harmonic continuation of the Newtonian potential of .
Analysis similar to that in the proof of Proposition 4.4 shows that the result is also valid for the solutions of (4.10).
Corollary 4.6**.**
Let be a viscosity solution to (4.10), then the statement of Theorem 4.3 holds for too.
5. Quadruple junctions
Throughout this section we assume that is convex, satisfies and is a viscosity solution, see Section 3.
Lemma 5.1**.**
Assume hold and is convex. Let and be a rank-2 flat point such that the zero set of the polynomial approximates near [math]. Assume further that is non-degenerate at [math]. Then for every there is (for some ) such that whenever and .
Proof.
Let and denote . After rotation of coordinate system we can assume that contains away from some small neighborhood of (the green cones in Figure 1 represent that neighborhood).
Suppose the claim fails, then there is so that for every and some points we have
[TABLE]
We can choose so that for large there holds where .
Introduce the scaled functions
[TABLE]
Here we set . For both scalings we have that ’s are non-degenerate: for the first scaling it follows from Theorem 3.4 (our assuption on non-degeneracy), for the second one it follows that .
Moreover, by (5.1) there is such that
[TABLE]
There is a subsequence there is a Harnack chain where and , is independent of . Let . Since under hypotheses we have local bounds for all (see Theorem 7.1 [CC-Fully]) it follows that we can employ a customary compactness argument for viscosity solutions to infer that there is a function such that we have
[TABLE]
From Theorem 2.6 it follows that . Moreover, satisfies the equation in , hence from the strong maximum principle it follows that in . Consequently, depends only on implying that or which is a contradiction.
∎
Theorem 5.2**.**
Let be as in Lemma 5.1. Then in some neighbourhood of [math] the free boundary consists of four curves tangential to the zero set of the polynomial .
Proof.
Let . Clearly, it is enough to prove that there is such that . Suppose the claim fails. Then there is a sequence , . Let and consider
[TABLE]
Note that , and therefore by dichotomy (see Section 4) and non-degeneracy for some independent of .
By construction and since in it follows that there is such that . Consequently, and by Lemma 5.1
[TABLE]
Claim 5.3**.**
With the notation above we have
[TABLE]
To check this we first observe that thanks to the convexity and . Now consider then . Since is continuous and then one can easily check that
[TABLE]
because of convexity of and the estimate .
Note that
[TABLE]
Thus from (5.5) it follows that
[TABLE]
Consequently, we get
[TABLE]
Let then
[TABLE]
provided that is sufficiently large.
We see that is a subsolution, and hence so is . Consequently, applying the weak Harnack inequality [CC-Fully] we get
[TABLE]
This completes the proof of the claim.
Thus, as in the proof of Lemma 5.1, we can employ a customary compactness argument in so that and
[TABLE]
by Harnack chain and estimates in the Harnack chain domain (which joins with ). Since at free boundary is a line we can apply Hopf’s lemma to conclude that which is a contradiction. ∎
6. Existence of homogenous blow-ups
In this section we show that if the free boundary is a cone then one can blow-up the solution at the vertex so that the limit is a homogeneous function. We start with a doubling inequality which provides a bound for the rate of the scaling at the vertex.
Lemma 6.1**.**
Assume hold and is concave. Let , such that is smooth. Let be the solution to the Dirichlet problem in and on where
[TABLE]
Then there is a constant such that
[TABLE]
Proof.
Existence of follows from the Perron’s method [CC-Fully].
Consider the barrier for some to be fixed below. We have
[TABLE]
Consequently, in the ring we have from and that
[TABLE]
provided that .
Since is concave function of and is convex in such that and , then it follows that on . Moreover, by the maximum principle we have on . Thus on , which in conjunction with and the comparison principle implies that in .
Furthermore, for we have , hence (6.1) is true for every . On the other hand on (where ) we have
[TABLE]
where the last line follows from the mean value theorem. Thus (6.1) holds on with . Applying the comparison principle to and the result follows. ∎
With the help of Lemma 6.1 we can prove the existence of a homogeneous solution of the form vanishing on the boundary of the cone .
Theorem 6.2**.**
There is and satisfying .
Proof.
First we want to compare with its scalings in order to obtain two sided bounds. From (6.1), the strong maximum principle and Hopf’s lemma (see [Giga]), we derive that there is a such that
[TABLE]
for all . This and the weak comparison principle imply that (6.3) holds for all . Consequently, we can use the -estimate of [CC-Fully] and (6.1) (combined with the barrier argument in [Wang]) in order to obtain a and a sequence of tending to zero such that
[TABLE]
in the sense . Moreover, in , on , and is a viscosity solution of in . By the strong maximum principle (see Lemma 2.3) and Hopf’s lemma [Giga], , in , and on .
Let . By Lemma 2.7 it is enough to prove the existence of a satisfying
[TABLE]
In order to prove (6.5) let us define . By (6.3) . Note that , if and thus
[TABLE]
In order to show (6.5), we set
[TABLE]
By the weak comparison principle, is decreasing with respect to . This and (6.4) imply that
[TABLE]
Let us suppose that (6.5) is not true. Then, we can use (6.6), the strong comparison principle and Hopf’s comparison principle (see Section 2, Lemmata 2.3 and 2.4) to obtain a such that
[TABLE]
This and (6.4) show that
[TABLE]
for some . By the weak comparison principle, (6.7) holds for all . This, however, is a contradiction to the definition of . Hence, (6.5) must be true. ∎
The homogeneous solutions , constructed in Theorem 6.2, provide two-sided control for the scalings of the solutions of in the cone .
Theorem 6.3**.**
Let be a viscosity solution of in the cone . Then then for every sequence , there exists a subsequence such that the functions
[TABLE]
converges locally uniformly to .
Proof.
Let then by the boundary Harnack principle (2.4) there is a constant such that
[TABLE]
We want to prove that there is a subsequence of such that
[TABLE]
in .
Define
[TABLE]
By (6.8) . From the weak comparison principle (as in the proof of Theorem 6.2), one derives that is decreasing with respect to . Consequently, the limit
[TABLE]
exists and it is positive. The -estimates of [CC-Fully], regularity result and (6.8) imply that there is a subsequence of and a such that
[TABLE]
in the sense of . Moreover, on , solves in and
[TABLE]
Now, suppose that is not identical to , in . Then, (6.11), the strong comparison principle and Hopf’s comparison principle (see Section 2, Lemmata 2.3 and 2.4) imply that there is a such that
[TABLE]
This and (6.10) show that
[TABLE]
for some . The weak comparison principle shows that this is true, also in . This, however, is a contradiction to the definition of . Hence, , in , and (6.9) is true. ∎
References
