# Frequency and Time Domain Analysis ofsRNA-based Treatment for   Inflammatory BowelDisease

**Authors:** Arman Karshenas, Joseph Windo, Bhuvana, Jonathan Stocks, Adrian, Kozhevnikov, Jhanna Kryukova, Eleanor Beard, Laurel Constanti Crosby, Max, Taylor

arXiv: 1906.05024 · 2019-06-13

## TL;DR

This paper validates a complex reaction pathway for treating Inflammatory Bowel Disease using frequency and time domain analysis, highlighting the potential of sRNA-based probiotics for future therapeutic applications.

## Contribution

It introduces a novel frequency and time domain analysis approach to verify a proposed reaction pathway for IBD treatment, emphasizing the role of negative feedback loops.

## Key findings

- Negative feedback loop significantly influences the reaction pathway.
- Proposed probiotics show promising potential for IBD treatment.
- Frequency domain analysis confirms pathway validity.

## Abstract

The validity of a complex reaction pathway proposed to treat Inflammatory Bowel Disease (IBD) was verified by a comprehensive time and frequency domain analysis. The model was taken to the frequency domain to study the effect and the significance of the negative feedback loop introduced by the reaction pathways. It could be shown that such proposed probiotics have very interesting potentials that could be used extensively in the near future.

## Full text

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## Figures

16 figures with captions in the complete paper: https://tomesphere.com/paper/1906.05024/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/1906.05024/full.md

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Source: https://tomesphere.com/paper/1906.05024