Method for Assessing the Fidelity of Optical Diffraction Tomography Reconstruction Methods

TL;DR

This paper introduces an experimental method using structured illumination and a spatial light modulator to evaluate the accuracy of optical diffraction tomography reconstruction algorithms without needing ground truth data.

Contribution

It presents the first assessment technique employing structured illumination to quantify the error of different refractive index reconstruction algorithms experimentally.

Findings

First experimental assessment method for reconstruction accuracy

Quantifies errors without ground truth using optical phase conjugation

Applicable to various reconstruction algorithms

Abstract

We use a spatial light modulator in a diffraction tomographic system to assess the accuracy of different refractive index reconstruction algorithms. Optical phase conjugation principles through complex media, allows us to quantify the error for different refractive index reconstruction algorithms without access to the ground truth. To our knowledge, this is the first assessment technique that uses structured illumination experimentally to test the accuracy of different reconstruction schemes.