Persistence of Delayed Complex Balanced Chemical Reaction Networks

TL;DR

This paper establishes new criteria for the persistence and stability of delayed complex balanced chemical reaction networks, extending previous results to systems with time delays and specific stoichiometric properties.

Contribution

It introduces two sufficient conditions for persistence in delayed complex balanced systems and proves global stability for certain classes, extending classical results to delayed networks.

Findings

Delayed systems with specific stoichiometric properties are persistent.

Systems with 2-dimensional stoichiometric subspace are persistent.

Certain classes are globally asymptotically stable at positive equilibrium.

Abstract

In this paper, we derive two sufficient conditions to diagnose the persistence of two classes of delayed complex balanced chemical reaction network systems equipped with mass-action kinetics. One class is identified by $\dim Z_W=\dim\mathscr{S}-1$ ($Z_W$ is defined by \ref{eq:g} while $\mathscr{S}$ is the stoichiometric subspace of the network), the other class is identified through $\dim Z_W=0$ for any semilocking species set $W$ in the network. Then we also derive that delayed complex balanced systems with 2-d stoichiometric subspace are persistent. The results recur those proposed by Anderson et al. [D. F. Anderson, \textit{SIAM J. Appl. Math.}, 68 (2008), pp. 1464-1476; D. F. Anderson and A. Shiu, \textit{SIAM J. Appl. Math.}, 70 (2010), pp. 1840-1858] for checking the persistence of complex balanced reaction network systems without time delay. Further, we prove the above mentioned two classes of network systems are globally asymptotically stable at the corresponding positive equilibrium if the trajectory starts from a positive initial function. We illustrate the analysis by two numerical examples.