# Enhanced stability of the focus obtained by wavefront optimization in dynamical scattering media

## TL;DR

This paper demonstrates that wavefront optimization can produce a focus with enhanced stability in dynamical scattering media, outperforming surrounding speckle stability, which is promising for deep in vivo imaging.

## Contribution

It provides experimental evidence that wavefront shaping can achieve more stable focusing than speckle decorrelation in dynamic scattering environments.

## Key findings

- Focus stability exceeds speckle decorrelation in certain conditions
- Wavefront optimization extends focus lifetime in dynamic media
- Heterogeneous stability of scattering sequences observed

## Abstract

Focusing scattered light using wavefront shaping provides interesting perspectives to image deep in opaque samples, as e.g. in nonlinear fluorescence microscopy. Applying these technics to in vivo imaging remains challenging due to the short decorrelation time of the speckle in depth, as focusing and imaging has to be achieved within the order of the decorrelation time. In this paper, we experimentally study the focus lifetime after focusing through dynamical scattering media, when iterative wavefront optimization and speckle decorrelation occur over the same timescale. We show experimental situations with heterogeneous stability of the scattering sequences, where the focus presents significantly higher stability than the surrounding speckle.

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Source: https://tomesphere.com/paper/1905.03757