# Real-time measurement with a fiber optical surface plasmon resonance sensor for biochemical interaction analysis

## TL;DR

This paper presents a fiber optical surface plasmon resonance sensor capable of real-time biochemical interaction analysis, demonstrating its effectiveness with alcohol-water mixtures and emphasizing its potential for compact biosensing applications.

## Contribution

The work introduces a novel fiber SPR sensor system with integrated real-time data processing and noise reduction, advancing portable biochemical sensing technology.

## Key findings

- Achieved spectral resolution of 0.2 nm.
- Successfully measured alcohol-water mixtures in real-time.
- Demonstrated potential for compact biosensor development.

## Abstract

In this paper we report a fiber optical sensor system based on surface plasmon resonance (SPR) with real-time response for biochemical interaction analysis. The fiber sensor is constructed from a multi-mode fiber with plastic cladding. To facilitate the measurement, a software program is developed which integrates the data acquisition and processing for real-time feedback. Polynomial fitting is implemented to smooth out the noise in the transmission ratio and a spectral resolution of 0.2 nm is achieved. Ethyl alcohol and water mixtures with different concentrations are measured to demonstrate the system's real-time capability. This work is essential for the development of a compact, real-time fiber SPR biosensor.