An injectable dosimeter for small animal irradiations

TL;DR

This paper introduces a new injectable in-vivo dosimeter using glass-encapsulated TLD rods for accurate dose measurement in small animal irradiations, allowing for dose validation in freely moving mice.

Contribution

The novel injectable dosimeter enables in vivo dose validation in small animals, improving accuracy in complex irradiation scenarios.

Findings

Reliable dose reconstruction within 10% of nominal dose

Successful injection and use in 30 mice

Applicable for inhomogeneous radiation fields

Abstract

We have developed a novel in-vivo dosimeter based on glass encapsulated TLD rods. These encapsulated rods can be injected into mice and used for validating doses to an individual mouse in a protracted irradiation scenario where the mouse is free to move in an inhomogenous radiation field. Data from 30 irradiated mice shows a reliable dose reconstruction within 10% of the nominal delivered dose.