# Computing on actin bundles network

## TL;DR

This paper proposes a novel approach to computing using actin bundles by leveraging excitation wave propagation to implement Boolean logic circuits, aligning with biological gate distributions.

## Contribution

It introduces a relaxed model of actin network computing based on excitation waves on actin bundles, enabling circuit implementation with arbitrary electrode arrangements.

## Key findings

- Feasible implementation of Boolean gates on actin networks.
- Matching of gate frequency distributions with biological substrates.
- Potential for bio-inspired computing architectures.

## Abstract

Actin filaments are conductive to ionic currents, mechanical and voltage solitons. These travelling localisations can be utilised in making the actin network executing specific computing circuits. The propagation of localisations on a single actin filament is experimentally unfeasible, therefore we propose a `relaxed' version of the computing on actin networks by considering excitation waves propagating on actin bundles. We show that by using an arbitrary arrangement of electrodes it is possible to implement two-inputs-one-output circuits. Frequencies of the Boolean gates' detection in actin network match an overall distribution of gates discovered in living substrates.