Mapping the Human Body at Cellular Resolution -- The NIH Common Fund Human BioMolecular Atlas Program
Michael P Snyder, Shin Lin, Amanda Posgai, Mark Atkinson, Aviv Regev,, Jennifer Rood, Orit Rosen, Leslie Gaffney, Anna Hupalowska, Rahul Satija,, Nils Gehlenborg, Jay Shendure, Julia Laskin, Pehr Harbury, Nicholas A, Nystrom, Ziv Bar-Joseph, Kun Zhang, Katy B\"orner, Yiing Lin
TL;DR
HuBMAP aims to create a comprehensive 3D cellular and molecular map of the human body at single-cell resolution, integrating advanced technologies and collaborative efforts over seven years.
Contribution
This project develops a framework for detailed spatial mapping of human tissues at cellular resolution, combining new technologies and collaborative data sharing.
Findings
Development of 3D tissue mapping technologies
Creation of a comprehensive human body atlas
Integration of spatial and molecular data
Abstract
Transformative technologies are enabling the construction of three dimensional (3D) maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible 3D molecular and cellular atlas of the human body, in health and various disease settings.
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