# Clustering-Correcting Codes

**Authors:** Tal Shinkar, Eitan Yaakobi, Andreas Lenz, Antonia Wachter-Zeh

arXiv: 1903.04122 · 2019-03-12

## TL;DR

This paper introduces clustering-correcting codes designed for DNA storage systems, enabling accurate strand clustering despite index errors, with theoretical bounds and a minimal redundancy construction.

## Contribution

It proposes a novel coding scheme that links index similarity to data dissimilarity, improving error resilience in unordered DNA data storage.

## Key findings

- Established bounds on code size for clustering-correcting codes
- Provided an explicit construction with only one bit of redundancy
- Demonstrated effectiveness in error-prone clustering scenarios

## Abstract

A new family of codes, called clustering-correcting codes, is presented in this paper. This family of codes is motivated by the special structure of data that is stored in DNA-based storage systems. The data stored in these systems has the form of unordered sequences, also called strands, and every strand is synthesized thousands to millions of times, where some of these copies are read back during sequencing. Due to the unordered structure of the strands, an important task in the decoding process is to place them in their correct order. This is usually accomplished by allocating a part of the strand for an index. However, in the presence of errors in the index field, important information on the order of the strands may be lost.   Clustering-correcting codes ensure that if the distance between the index fields of two strands is small, then there will be a large distance between their data fields. It is shown how this property enables to place the strands together in their correct clusters even in the presence of errors. We present lower and upper bounds on the size of clustering-correcting codes and an explicit construction of these codes which uses only a single bit of redundancy.

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/1903.04122/full.md

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Source: https://tomesphere.com/paper/1903.04122