# An analysis of a mathematical model describing the growth of a tumor   treated with chemotherapy

**Authors:** Anderson L.A. de Araujo, Artur C. Fassoni, Lu\'is F. Salvino

arXiv: 1902.01502 · 2019-02-06

## TL;DR

This paper analyzes a mathematical model combining ODEs and PDEs to describe tumor and normal cell growth under localized chemotherapy, providing theoretical results and numerical simulations.

## Contribution

It introduces a novel mixed ODE-PDE model for tumor growth with localized drug delivery, including existence, uniqueness, and simulation results.

## Key findings

- Model exhibits different behaviors depending on parameters.
- Existence and uniqueness of solutions are established.
- Numerical simulations illustrate tumor response to therapy.

## Abstract

We present a mathematical analysis of a mixed ODE-PDE model describing the spatial distribution and temporal evolution of tumor and normal cells within a tissue subject to the effects of a chemotherapeutic drug. The model assumes that the influx of chemotherapy is restricted to a limited region of the tissue, mimicking a blood vessel passing transversely. We provide results on the existence and uniqueness of the model solution and numerical simulations illustrating different model behaviors.

## Full text

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## Figures

38 figures with captions in the complete paper: https://tomesphere.com/paper/1902.01502/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/1902.01502/full.md

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Source: https://tomesphere.com/paper/1902.01502