# Diamond nano-pillar arrays for quantum microscopy of neuronal signals

## TL;DR

This paper introduces diamond nanopillar arrays with NV centers to enhance quantum microscopy for neuronal signals, enabling nanoscale, long-term, wide-field measurements in neuroscience.

## Contribution

It presents a novel diamond nanopillar array design that improves NV sensor sensitivity and neuron growth coordination for advanced neural electromagnetics studies.

## Key findings

- Enhanced light collection efficiency in nanopillars
- Improved neuron growth at nanopillar tips
- First simulation of nanoscale neuronal electric and magnetic fields

## Abstract

Modern neuroscience is currently limited in its capacity to perform long term, wide-field measurements of neuron electromagnetics with nanoscale resolution. Quantum microscopy using the nitrogen vacancy centre (NV) can provide a potential solution to this problem with electric and magnetic field sensing at nano-scale resolution and good biocompatibility. However, the performance of existing NV sensing technology does not allow for studies of small mammalian neurons yet. In this paper, we propose a solution to this problem by engineering NV quantum sensors in diamond nanopillar arrays. The pillars improve light collection efficiency by guiding excitation/emission light, which improves sensitivity. More importantly, they also improve the size of the signal at the NV by removing screening charges as well as coordinating the neuron growth to the tips of the pillars where the NV is located. Here, we provide a growth study to demonstrate coordinated neuron growth as well as the first simulation of nano-scopic neuron electric and magnetic fields to assess the enhancement provided by the nanopillar geometry.