# Healthy versus pathological learning transferability in shoulder muscle MRI segmentation using deep convolutional encoder-decoders

## TL;DR

This study explores deep learning for automatic shoulder muscle MRI segmentation, focusing on transferability from healthy to pathological data and improving accuracy with pre-trained encoders, aiding clinical diagnosis.

## Contribution

It demonstrates the feasibility of using limited annotated data and transfer learning to enhance pathological shoulder muscle segmentation accuracy.

## Key findings

- Achieved Dice scores up to 82.8% for certain muscles.
- Pre-trained encoders improve segmentation performance.
- Transfer learning from healthy to pathological data is effective.

## Abstract

Automatic segmentation of pathological shoulder muscles in patients with musculo-skeletal diseases is a challenging task due to the huge variability in muscle shape, size, location, texture and injury. A reliable fully-automated segmentation method from magnetic resonance images could greatly help clinicians to plan therapeutic interventions and predict interventional outcomes while eliminating time consuming manual segmentation efforts. The purpose of this work is three-fold. First, we investigate the feasibility of pathological shoulder muscle segmentation using deep learning techniques, given a very limited amount of available annotated pediatric data. Second, we address the learning transferability from healthy to pathological data by comparing different learning schemes in terms of model generalizability. Third, extended versions of deep convolutional encoder-decoder architectures using encoders pre-trained on non-medical data are proposed to improve the segmentation accuracy. Methodological aspects are evaluated in a leave-one-out fashion on a dataset of 24 shoulder examinations from patients with obstetrical brachial plexus palsy and focus on 4 different muscles including deltoid as well as infraspinatus, supraspinatus and subscapularis from the rotator cuff. The most relevant segmentation model is partially pre-trained on ImageNet and jointly exploits inter-patient healthy and pathological annotated data. Its performance reaches Dice scores of 82.4%, 82.0%, 71.0% and 82.8% for deltoid, infraspinatus, supraspinatus and subscapularis muscles. Absolute surface estimation errors are all below 83mm$^2$ except for supraspinatus with 134.6mm$^2$. These contributions offer new perspectives for force inference in the context of musculo-skeletal disorder management.