# Lack of an equation of state for the nonequilibrium chemical potential of gases of active particles in contact

## TL;DR

This paper investigates the concept of nonequilibrium chemical potential in active particle gases, revealing it lacks an equation of state and depends on potential details, challenging equilibrium thermodynamics assumptions.

## Contribution

It demonstrates that the nonequilibrium chemical potential for active particles does not follow an equation of state and depends on potential barrier details, unlike equilibrium systems.

## Key findings

- Chemical potential depends on potential barrier shape
- No equation of state for the nonequilibrium chemical potential
- Maxwell relation is invalid in this context

## Abstract

We discuss the notion of nonequilibrium chemical potential in gases of non-interacting active particles filling two compartments separated by a potential energy barrier. Different types of active particles are considered: run-and-tumble particles, active Brownian particles, and active Brownian particles with a stochastic reorientation along an external field. After recalling some analytical results for run-and-rumble particles in one dimension, we focus on the two-dimensional case and obtain a perturbative expression of the density profile in the limit of a fast reorientation dynamics, for the three models of active particles mentioned above. Computing the chemical potentials of the non-equilibrium systems in contact from the knowledge of the stationary probability distribution of the whole system ---which agrees with a recently proposed general definition of the chemical potential in non-equilibrium systems in contact--- we generically find that the chemical potential lacks an equation of state, in the sense that it depends on the detailed shape of the potential energy barrier separating the compartments and not only on bulk properties, at odds with equilibrium. This situation is reminiscent of the properties of the mechanical pressure in active systems. We also argue that the Maxwell relation is no longer valid and cannot be used to infer the nonequilibrium chemical potential from the knowledge of the mechanical pressure.