Properties of Chromatin in Human Cells as Characteristics of the State of Human Organism: A Review

TL;DR

This review discusses how chromatin properties in human cells reflect the overall health and disease states of the organism, highlighting its potential for medical assessment and disease diagnosis.

Contribution

It synthesizes existing knowledge on chromatin's role in health, emphasizing its use as a biomarker for organismal state and disease severity.

Findings

Chromatin state correlates with organism health.

Heterochromatin granules can assess disease severity.

Chromatin analysis aids in medical and athletic evaluations.

Abstract

The state of chromatin in individual cells is directly related to the state of the whole organism and may be used for assessment of the state of the whole organism. Many hereditary diseases are connected with chromatin rearrangements. Chromatin distribution in cell nucleus is an important characteristic which may be applied for determination of disease gravity. The method of determination of the quantity of heterochromatin granules in buccal epithelium cells may be applied in the assessment of the state of human organism during sportive trainings and medical treatment.