Stochastic Models for Cochlear Instabilities

TL;DR

This paper models cochlear dynamics as a stochastic system of coupled oscillators, revealing that small parameter variations can cause instability and spontaneous oscillations, with predictions validated by simulations.

Contribution

It introduces a stochastic model of cochlear dynamics showing extreme sensitivity to small parameter changes and provides a simulation-free method to predict stability thresholds.

Findings

Small stochastic parameter variations destabilize cochlear dynamics.

Theoretical predictions match nonlinear stochastic simulations.

Spontaneous oscillations arise from local amplification and spatial coupling.

Abstract

We investigate instabilities in a stochastic mathematical model of cochlear dynamics. The cochlea is modeled as a spatio-temporal dynamical system made up of a spatially distributed array of coupled oscillators, together with the cochlear amplification mechanism. We consider a setting where the cochlear amplifier has relatively small spatially and temporally varying stochastic parameters. It is shown that relatively small parameter variations (five to four orders of magnitude smaller than the nominal values) are sufficient to destabilize the dynamics and induce spontaneous oscillations. This extreme sensitivity of the cochlear dynamics appears to be due to a combination of the local cochlear amplification mechanism, as well as the spatial coupling of the distributed resonators. We use an analysis technique which allows for a simulation-free prediction of the stability thresholds, as well as the statistics of the spontaneous oscillations. We verify our theoretical predictions using full non- linear stochastic simulations which appear to be in very good agreement with our theory.