Concentration-adjustable micromixer using droplet injection into a microchannel

TL;DR

This paper introduces a new micromixing method that uses droplet injection into microchannels, allowing precise and adjustable mixing levels by controlling droplet injection parameters, which is useful for sample concentration control.

Contribution

The study presents a novel droplet injection technique for micromixing that enables simple, stable, and adjustable concentration control by varying injection frequency and droplet volume fraction.

Findings

Mixing level increases with injection frequency.

Mixing level increases with droplet-diameter-to-channel-width ratio.

Mixing level is linearly related to droplet volume fraction.

Abstract

A novel micromixing technique that exploit a thrust of droplets into the mixing interface is developed. The technique enhances the mixing by injecting immiscible droplets in a mixing channel and the methodology enables a control of the mixing level simply by changing the droplet injection frequency. We experimentally characterize the mixing performance with various droplet injection frequencies, channel geometries, and diffusion coefficients. Consequently, it is revealed that the mixing level increases with the injection frequency, the droplet-diameter-to-channel-width ratio, and the diffusion coefficient. Moreover, the mixing level is found to be a linear function of the droplet volume fraction in the mixing section. The results suggest that the developed technique can produce a large amount of sample solution whose concentration is arbitrary and precisely controllable with a simple and stable operation.