Frontiers in Pigment Cell and Melanoma Research

TL;DR

This paper reviews emerging frontiers in melanocyte and melanoma research, highlighting advances in immunotherapy, genomics, dermatology, and pigment biology, and discusses current challenges and future opportunities in these fields.

Contribution

It provides a comprehensive overview of recent advances and identifies key challenges and future directions across clinical and basic research in melanocyte and melanoma sciences.

Findings

Advances in melanoma immunotherapy and genomics.

Emerging frontiers in pigment biophysics and evolution.

Challenges in clinical and basic melanocyte research.

Abstract

We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current approaches to research in melanoma and the dermatological sciences. We focus on four themes: (1) clinical melanoma research, (2) basic melanoma research, (3) clinical dermatology, and (4) basic pigment cell research, with the goal of outlining current highlights, challenges, and frontiers associated with pigmentation and melanocyte biology. Significantly, this document encapsulates important advances in melanocyte and melanoma research including emerging frontiers in melanoma immunotherapy, medical and surgical oncology, dermatology, vitiligo, albinism, genomics and systems biology, epidemiology, pigment biophysics and chemistry, and evolution.