ZICS: an application for calculating the stationary probability distribution of stochastic reaction networks

TL;DR

ZICS is a free application that implements a numerical method to efficiently compute the stationary probability distributions of stochastic reaction networks, aiding biological system analysis.

Contribution

The paper introduces ZICS, a free software tool based on the ZI-closure scheme, providing a practical solution for calculating stationary distributions in stochastic reaction networks.

Findings

Enables efficient computation of stationary distributions.

Supports analysis of biological stochastic systems.

Provides an accessible tool for researchers.

Abstract

Stochastic formalisms are necessary to describe the behavior of many biological systems. However, there remains a lack of numerical methods available to calculate the stationary probability distributions of stochastic reaction networks. We have previously development a numerical approach to calculate stationary probability distributions of stochastic networks, named ZI closure scheme. In this work, we present a free applications based on ZI-closure scheme, called ZICS.