Rigorous derivation of the nonlocal reaction-diffusion FitzHugh-Nagumo system
Joachim Crevat, Gr\'egory Faye (IMT), Francis Filbet (IMT)

TL;DR
This paper rigorously derives the nonlocal reaction-diffusion FitzHugh-Nagumo system from a spatially extended kinetic model using a relative entropy method, establishing a rigorous link between kinetic and reaction-diffusion models.
Contribution
It introduces a kinetic FitzHugh-Nagumo model with local interactions and proves its hydrodynamic limit converges to the classical nonlocal reaction-diffusion system.
Findings
Hydrodynamic limit converges to the reaction-diffusion system
Relative entropy method effectively links kinetic and macroscopic models
Provides a rigorous mathematical foundation for the derivation
Abstract
We introduce a spatially extended transport kinetic FitzHugh-Nagumo model with forced local interactions and prove that its hydrodynamic limit converges towards the classical nonlocal reaction-diffusion FitzHugh-Nagumo system. Our approach is based on a relative entropy method, where the macroscopic quantities of the kinetic model are compared with the solution to the nonlocal reaction-diffusion system. This approach allows to make the rigorous link between kinetic and reaction-diffusion models.
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Taxonomy
TopicsAdvanced Thermodynamics and Statistical Mechanics · Mathematical Biology Tumor Growth · Theoretical and Computational Physics
