A method of reconstruction for X-ray phase contrast imaging with arbitrary Fresnel number

TL;DR

This paper introduces a novel lensless X-ray imaging technique that enables one-step reconstruction of the refractive index from hologram intensity data, improving contrast in biological tissue imaging.

Contribution

It presents a new general method for one-step phase retrieval in X-ray phase contrast imaging with arbitrary Fresnel number, addressing detector limitations.

Findings

Enhanced contrast in biological tissue imaging.

Effective one-step phase retrieval method.

Applicable to arbitrary Fresnel numbers.

Abstract

New lensless diffractive X-ray technic for micro-scale imaging of biological tissue is based on quantitative phase retrieval schemes. By incorporating refraction, this method yields improved contrast compared to purely absorption-based radiography but involves a phase retrieval problem since of physical limitation of detectors. A general method is proposed in this paper for one step reconstruction of the ray integral of complex refractive index of an optically weak object from intensity distribution of the hologram.