Journey to the Centre of the Earth: Jule Vernes' dream in the laboratory from an NMR perspective

TL;DR

This paper reviews the challenges and recent advances in high pressure nuclear magnetic resonance (NMR), highlighting its potential despite technical difficulties like low signal and harsh conditions.

Contribution

It provides a comprehensive overview of high pressure NMR research, emphasizing its development and current state in the context of challenging experimental conditions.

Findings

High pressure NMR faces significant technical challenges.

Recent advances have improved signal detection under extreme conditions.

The review highlights future directions for high pressure NMR research.

Abstract

High pressure nuclear magnetic resonance is among the most challenging fields of research for every NMR spectroscopist due to inherently low signal intensities, inaccessible and ultra-small samples, and overall extremely harsh conditions in the sample cavity of modern high pressure vessels. This review aims to provide a comprehensive overview of the topic of high pressure research and its fairly young and brief relationship with NMR.