Preface to Introduction to Protein Structural Bioinformatics

TL;DR

This book introduces the field of Structural Bioinformatics, covering computational techniques for analyzing, predicting, and simulating three-dimensional protein structures, aimed at providing practical knowledge for newcomers.

Contribution

It fills the gap of an introductory resource in Structural Bioinformatics, combining theory with practical guidance on computational methods for protein analysis.

Findings

Overview of computational techniques for protein analysis

Guidance on when and how to use structural bioinformatics methods

Focus on protein structure quantification, prediction, and dynamics

Abstract

While many good textbooks are available on Protein Structure, Molecular Simulations, Thermodynamics and Bioinformatics methods in general, there is no good introductory level book for the field of Structural Bioinformatics. This book aims to give an introduction into Structural Bioinformatics, which is where the previous topics meet to explore three dimensional protein structures through computational analysis. We provide an overview of existing computational techniques, to validate, simulate, predict and analyse protein structures. More importantly, it will aim to provide practical knowledge about how and when to use such techniques. We will consider proteins from three major vantage points: Protein structure quantification, Protein structure prediction, and Protein simulation & dynamics.