Shape deformation of a vesicle under axisymmetric non-uniform alternating electric field

TL;DR

This study investigates how vesicles deform under axisymmetric non-uniform alternating electric fields, highlighting the transition from entropic to enthalpic tension and its dependence on electrical properties and frequency.

Contribution

It introduces a combined entropic and enthalpic tension model for vesicle deformation under electric fields, revealing shape dependencies and transition mechanisms.

Findings

Vesicle shape depends on conductivity ratio and electric field frequency.

Transition between tension regimes is influenced by excess area.

Maxwell stress approach explains dielectrophoretic velocity.

Abstract

Non-uniform fields are commonly used to study vesicle dielectrophoresis and can be used to hitherto relatively unexplored areas of vesicle deformation and electroporation. A common but perplexing problem in vesicle dynamics is the cross over from the entropic to enthalpic (stretching) tension during vesicle deformation. A lucid demonstration of this concept is provided by the study of vesicle deformation and dielectrophoresis under axisymmetric quadrupole electric field. Small deformation theory incorporating the Maxwell stress approach is used (employing area and volume conservation constraints) to estimate the dielectrophoretic velocity. The entropic and enthalpic tensions are implemented to understand vesicle electrohydrodynamics in low and high tension limits. The shapes obtained using the entropic and the enthalpic approaches, show significant differences. A strong dependence of the final vesicle shapes on the ratio of electrical conductivities of the fluids inside and outside the vesicle as well as on the frequency of the applied quadrupole electric field is observed which could be used to estimate electromechanical properties of the vesicle. Moreover, an excess area dependent transition between the entropic and enthalpic regimes is observed. The Maxwell stress approach, used in this work, indicates that Clausius-Mossotti factor obtained by the dipole moment method together with the drag on a rigid sphere explains vesicle dielectrophoresis. Interestingly, the coupling of hydrodynamic and electric stress, important in drops is absent in vesicle dielectrophoresis to linear order.