Diffusive Molecular Communications with Reactive Signaling
Vahid Jamali, Nariman Farsad, Robert Schober, and Andrea Goldsmith

TL;DR
This paper develops detection algorithms for molecular communication systems with reactive molecules, demonstrating improved performance and reduced interference through reaction-based signaling, validated by simulations and an efficient channel response computation method.
Contribution
It introduces the first ML detector for reactive molecular communication, proposes suboptimal detectors, and develops an efficient algorithm for channel response calculation.
Findings
Reactive signaling reduces inter-symbol interference.
Proposed detectors approach the genie-aided ML performance.
Reactive MC outperforms non-reactive MC in simulations.
Abstract
This paper focuses on molecular communication (MC) systems where the signaling molecules may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can realize the concept of constructive and destructive signal superposition, which leads to favorable properties such as inter-symbol interference (ISI) reduction and avoiding environmental contamination due to continuous release of molecules into the channel. This work first derives the maximum likelihood (ML) detector for a binary MC system with reactive signaling molecules under the assumption that the detector has perfect knowledge of the ISI. The performance of this genie-aided ML detector yields an upper bound on the performance of any practical detector. In addition, two suboptimal detectors of different complexity are proposed. The proposed ML detector as well as…
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