Separation of Water and Fat Magnetic Resonance Imaging Signals Using Deep Learning with Convolutional Neural Networks

TL;DR

This paper introduces a deep learning approach using convolutional neural networks, specifically U-Net, for water-fat separation in MRI, demonstrating comparable accuracy and improved signal-to-noise ratio over traditional methods.

Contribution

The study presents a novel deep learning method for MR water-fat separation that works with complex and magnitude images, achieving results similar to conventional techniques with higher efficiency.

Findings

Water-fat separation results visually comparable to conventional methods.

Predicted quantitative values highly correlated with traditional methods (R2 >= 0.97).

DL images showed a 14% higher signal-to-noise ratio.

Abstract

Purpose: A new method for magnetic resonance (MR) imaging water-fat separation using a convolutional neural network (ConvNet) and deep learning (DL) is presented. Feasibility of the method with complex and magnitude images is demonstrated with a series of patient studies and accuracy of predicted quantitative values is analyzed. Methods: Water-fat separation of 1200 gradient-echo acquisitions from 90 imaging sessions (normal, acute and chronic myocardial infarction) was performed using a conventional model based method with modeling of R2* and off-resonance and a multi-peak fat spectrum. A U-Net convolutional neural network for calculation of water-only, fat-only, R2* and off-resonance images was trained with 900 gradient-echo Multiple and single-echo complex and magnitude input data algorithms were studied and compared to conventional extended echo modeling. Results: The U-Net ConvNet was easily trained and provided water-fat separation results visually comparable to conventional methods. Myocardial fat deposition in chronic myocardial infarction and intramyocardial hemorrhage in acute myocardial infarction were well visualized in the DL results. Predicted values for R2*, off-resonance, water and fat signal intensities were well correlated with conventional model based water fat separation (R2>=0.97, p<0.001). DL images had a 14% higher signal-to-noise ratio (p<0.001) when compared to the conventional method. Conclusion: Deep learning utilizing ConvNets is a feasible method for MR water-fat separationimaging with complex, magnitude and single echo image data. A trained U-Net can be efficiently used for MR water-fat separation, providing results comparable to conventional model based methods.