A five-decision testing procedure to infer on unidimensional parameter
Aaron McDaid, Zoltan Kutalik, Valentin Rousson

TL;DR
This paper introduces a five-decision testing procedure that combines the strengths of existing methods, enabling more efficient hypothesis testing with reduced sample sizes while accommodating plausible point hypotheses.
Contribution
It proposes a novel five-decision rule testing procedure that improves power and reduces sample size requirements compared to traditional and existing multi-decision tests.
Findings
Reduces sample size needed for statistical significance by about 20%.
Combines advantages of Kaiser and Jones-Tukey procedures.
Applicable when point null hypotheses are plausible.
Abstract
A statistical test can be seen as a procedure to produce a decision based on observed data, where some decisions consist of rejecting a hypothesis (yielding a significant result) and some do not, and where one controls the probability to make a wrong rejection at some pre-specified significance level. Whereas traditional hypothesis testing involves only two possible decisions (to reject or not a null hypothesis), Kaiser's directional two-sided test as well as the more recently introduced Jones and Tukey's testing procedure involve three possible decisions to infer on unidimensional parameter. The latter procedure assumes that a point null hypothesis is impossible (e.g. that two treatments cannot have exactly the same effect), allowing a gain of statistical power. There are however situations where a point hypothesis is indeed plausible, for example when considering hypotheses derived…
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Taxonomy
TopicsStatistical Methods in Clinical Trials · Advanced Statistical Methods and Models · Bayesian Modeling and Causal Inference
