Onset of natural selection in auto-catalytic heteropolymers

TL;DR

This paper presents a theoretical model demonstrating how simple physical systems of heteropolymers can spontaneously reduce information entropy and undergo natural selection, shedding light on the origins of life.

Contribution

It introduces a minimal physical model showing spontaneous entropy reduction and natural selection in heteropolymers, with implications for early life and evolution.

Findings

Spontaneous reduction of information entropy in heteropolymers.

Survival of a limited subset of sequences with exponential diversity.

Potential experimental implementations suggested.

Abstract

Reduction of information entropy along with ever-increasing complexity are among the key signatures of living matter. Understanding the onset of such behavior in early prebiotic world is essential for solving the problem of origins of life. To elucidate this transition, we study a theoretical model of information-storing heteropolymers capable of template-assisted ligation and subjected to cyclic non-equilibrium driving forces. We discover that this simple physical system undergoes a spontaneous reduction of the information entropy due to the competition of chains for constituent monomers. This natural-selection-like process ultimately results in the survival of a limited subset of polymer sequences. Importantly, the number of surviving sequences remains exponentially large, thus opening up the possibility of further increase in complexity due to Darwinian evolution. We also propose potential experimental implementations of our model using either biopolymers or artificial nano-structures.