Symbol Synchronization for Diffusion-Based Molecular Communications
Vahid Jamali, Arman Ahmadzadeh, and Robert Schober

TL;DR
This paper develops and compares multiple symbol synchronization schemes for molecular communication systems, addressing practical challenges like lack of internal clocks and variable symbol intervals, and evaluates their performance and complexity.
Contribution
It introduces novel synchronization frameworks for MC systems considering realistic constraints, deriving optimal and low-complexity schemes for reliable detection.
Findings
Optimal ML synchronization schemes serve as performance benchmarks.
Low-complexity schemes are effective for resource-limited MC systems.
Synchronization errors significantly impact detection accuracy.
Abstract
Symbol synchronization refers to the estimation of the start of a symbol interval and is needed for reliable detection. In this paper, we develop several symbol synchronization schemes for molecular communication (MC) systems where we consider some practical challenges which have not been addressed in the literature yet. In particular, we take into account that in MC systems, the transmitter may not be equipped with an internal clock and may not be able to emit molecules with a fixed release frequency. Such restrictions hold for practical nanotransmitters, e.g. modified cells, where the lengths of the symbol intervals may vary due to the inherent randomness in the availability of food and energy for molecule generation, the process for molecule production, and the release process. To address this issue, we develop two synchronization-detection frameworks which both employ two types of…
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