# Effects of interaction between nanopore and polymer on translocation time

## TL;DR

This study uses molecular dynamics simulations to analyze how nanopore-polymer interactions affect translocation time, revealing dependencies on pore size, binding energy, and initial conditions, with results aligning with previous scaling laws.

## Contribution

It provides new insights into how interaction energy and initial conditions influence polymer translocation times in nanopores, supported by detailed MD simulations.

## Key findings

- Translocation time increases with binding energy and pore diameter.
- Scaling exponent of force versus time is approximately -0.9531.
- Translocation time is highly sensitive to initial polymer conditions.

## Abstract

Here using LAMMPS molecular dynamics (MD) software, we simulate polymer translocation in 2 dimensions. We do the simulations for weak and moderate forces and for different pore diameters. Our results show that in both non-equilibrium and equilibrium initial conditions, translocation time will always increase by increasing binding energy and or increasing pore diameter. Moreover, scaling exponent of time versus force is -0.9531 in accordance to our predecessors. The comparison between equilibrium and non-equilibrium initial condition shows that the translocation time is very sensitive to the initial condition. Translocation time of the relaxed polymers for interaction energy of 8k_B T is smaller from the non-equilibrium case even in the small energy of 1k_B T.

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Source: https://tomesphere.com/paper/1706.05810