Muscle-Cell-Based "Living Diodes"
Uryan Isik Can, Neerajha Nagarajan, Dervis Can Vural, Pinar Zorlutuna

TL;DR
This paper introduces a novel bioelectronic diode constructed from living muscle and fibroblast cells, capable of unidirectional signal transmission, representing a significant advancement in biohybrid device design.
Contribution
It presents the design, fabrication, and characterization of the first living diode using muscle and fibroblast cells for unidirectional electrical signaling.
Findings
The living diode allows signal passage in one direction only.
The device demonstrates functional unidirectional electrical conduction.
This approach opens new avenues for biohybrid electronic components.
Abstract
A new type of diode that is made entirely of electrically excitable muscle cells and nonexcitable fibroblast cells is designed, fabricated, and characterized. These two cell types in a rectangular pattern allow the signal initiated on the excitable side to pass to the nonexcitable side, and not in the opposite direction.
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