Some Ageing Properties of Dynamic Additive Mean Residual Life Model
Suchismita Das, Asok K. Nanda

TL;DR
This paper introduces and studies a new dynamic additive mean residual life model with time-dependent covariates, analyzing its properties and illustrating its behavior through examples, to enhance understanding of failure time data analysis.
Contribution
The paper defines a novel dynamic additive mean residual life model with time-dependent covariates and investigates its closure properties under various aging classes.
Findings
Model exhibits specific closure properties under certain aging classes.
Examples demonstrate the model's behavior and applicability.
Provides insights into failure time data analysis with dynamic covariates.
Abstract
Although proportional hazard rate model is a very popular model to analyze failure time data, sometimes it becomes important to study the additive hazard rate model. Again, sometimes the concept of the hazard rate function is abstract, in comparison to the concept of mean residual life function. A new model called `dynamic additive mean residual life model' where the covariates are time-dependent has been defined in the literature. Here we study the closure properties of the model for different positive and negative ageing classes under certain condition(s). Quite a few examples are presented to illustrate different properties of the model.
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Taxonomy
TopicsStatistical Distribution Estimation and Applications · Reliability and Maintenance Optimization · Insurance, Mortality, Demography, Risk Management
Some Ageing Properties of Dynamic Additive Mean Residual Life Model111This article has been published in “Rashi (2017), Vol. 2, Issue 1, pp. 26-33”
Suchismita Das
303/304, Shri Raghunarayan CHS
MIDC Road
Thakurli(E), Mumbai
Asok K. Nanda222corresponding author: [email protected]; [email protected]
Department of Mathematics and Statistics
IISER Kolkata
(March 2017)
Abstract
Although proportional hazard rate model is a very popular model to analyze failure time data, sometimes it becomes important to study the additive hazard rate model. Again, sometimes the concept of the hazard rate function is abstract, in comparison to the concept of mean residual life function. A new model called ‘dynamic additive mean residual life model’ where the covariates are time-dependent has been defined in the literature. Here we study the closure properties of the model for different positive and negative ageing classes under certain condition(s). Quite a few examples are presented to illustrate different properties of the model.
Key Words and Phrases: Additive mean residual life function, ageing property.
AMS 2010 Classifications: Primary 62N05; Secondary 90B25.
1 Introduction
In the literature, a large number of papers deal with modeling and analyzing data on the time until occurrence of an event. These events sometimes represent the time to failure of a system of components or a living organism. Cox’s [2] proportional hazard rate model has been used to model failure time data. This model is very popular for analysis of right-censored data, and has been used for estimating the risk of failure associated with vector of covariates.
Although multiplicative hazards model is mostly studied in literature, it is important to study the additive hazard rate model as well. This is because from the public health point of view it is very important to study the risk difference than the risk ratio in describing the association between the risk factor and the occurrence of a disease, see, for instance, Breslow and Day [9, 10]. They have shown that additive hazard rate model fits certain type of data better than the proportional hazard model. Lin and Ying [3] have shown that the additive hazards model provides a simple structure for studying frailty models and interval-censored data, which are very difficult to deal with under the proportional hazards model. A family of proportional and of additive hazards models for the analysis of grouped survival data has been considered by Tibshirani and Ciampi [13]. Mckeague and Utikal [7] have developed goodness-of-fit tests for Cox’s proportional hazards model and Aalen’s additive risk model, and each model has been compared on an equal footing with the best fitted fully nonparametric model. Using generalized linear models (GLM), Hakulinen and Tenkanen [15] have shown how a proportional hazards regression model may be adapted to the relative survival rates. Bada, Berrade and Campos [4] have studied some ageing characteristics of additive and of proportional hazard mixing models. They have also studied the effect of mixing on stochastic ordering. Martinussen and Scheike [16] have compared the full Aalen additive hazards model and the change-point model, and discussed how to estimate the parameters of the change-point model. The analytical properties of additive hazards model have been studied by Nair and Sankaran [11]. They have compared the ageing properties of the baseline random variable and the induced random variable. Li and Ling [12] have discussed the ageing and the dependence properties in the additive hazard mixing model. Some stochastic comparisons have also been studied in this paper. Bin [6] has discussed regression analysis of failure time under the additive hazards model, when the regression coefficients are time-varying.
Sometimes the concept of hazard function becomes abstract, in comparison to the concept of mean residual life (MRL) function. The hazard rate is the instantaneous failure rate at any point of time, whereas the MRL summarizes the entire residual life. The MRL function has more intuitive appeal for modeling and analysis of failure data than the concept of hazard rate function. With this in mind, the additive mean residual life (AMRL) model has been developed. The AMRL model specifies that the MRL function associated with the covariates is the sum of the baseline MRL function and the constant representing the function of covariates. For example, a new drug prescribed to a patient may work well in the beginning of the treatment period, but after a certain time the effect of the drug may decrease. Then it is very important to know when and how fast the drug becomes ineffective, see, for instance, Bin [6]. AMRL model helps us design further studies to explore the treatment strategies for patients. In some practical situations, the covariates may not be constant over the whole time interval , but they may vary over different time intervals. Using this idea Das and Nanda [14] have developed a new model called dynamic additive mean residual life (DAMRL) model. They have studied the closure of this model under different stochastic orders.
In Section we give a brief description of the DAMRL model, Section provides some ageing classes under the DAMRL model with some illustrative examples, and Section concludes the manuscript.
Throughout the paper, increasing and decreasing properties of a function are not used in strict sense. For any twice differentiable function , we write and to denote the first and the second derivatives of with respect to , respectively. We denote by to mean that and have the same sign, whereas tells that is defined by .
2 Dynamic Additive Mean Residual Life Model
Let be a nonnegative random variable with finite mean, survival function and hazard rate function . Then the MRL is given by
[TABLE]
for such that .
Let be a nonnegative absolutely continuous random variables having MRL function . Then the AMRL model is given by
[TABLE]
where is a function of covariates, independent of such that is nonnegative for all . Das and Nanda [14] have shown that Additive Hazard Rate model and AMRL model in general do not imply one another. For some more work in this direction, one may refer to Yin and Cai [5], Sun and Zhang [8] and the references there in. If the covariates are time-dependent, the AMRL model reduces to dynamic AMRL model given by
[TABLE]
Before going to discuss some results we give a lemma without proof, which gives some conditions on c(t) [cf. Das and Nanda [14]].
Lemma 2.1
If two nonnegative random variables and satisfy (2.2), then the following conditions must be satisfied:
- (i)
* for all ;* 2. (ii)
* is a continuous function of ;* 3. (iii)
* is increasing in ;* 4. (iv)
if there does not exist any with , then .
Remark 2.1
It is easy to see that if is increasing in , then the condition () of Lemma 2.1 trivially holds, whereas when , for all , condition () of Lemma 2.1 automatically holds.
Again, it can be noted that
[TABLE]
3 Properties of Some Ageing Classes
Ageing is an inherent property of a unit that may be a system of components or a living organism. It is characterized by various quantities, viz., hazard rate, mean residual life etc. By ageing we generally mean the adverse effect of age on the random residual lifetime of a unit. To be specific, by ageing we generally mean positive ageing, which means that an older system has a shorter remaining lifetime, in some statistical sense, than a newer one. In this section we have studied the closure of different ageing properties such as IFR (increasing in failure rate), IFRA (increasing failure rate in average), NBU (new better than used), NBUFR (new better than used in failure rate), NBAFR (new better than used in failure rate average) and their duals with time-dependent covariate(s).
In this section we study the condition(s) under which and satisfying (2.2) share some ageing properties. The following theorem shows that under the model (2.2), the IFR (resp. DFR) property of is transmitted to the random variable under certain condition on c(t). Keep in mind that a random variable with failure rate function is said to be IFR (resp. DFR) if is increasing (resp. decreasing) in .
The following theorem states the conditions for to be IFR. Here we need to be positive.
Theorem 3.1
If the random variable is IFR, then the random variable satisfying (2.2) is IFR provided, for all ,
- (i)
* is increasing in ;* 2. (ii)
* is logconvex.*
: Differentiating (2.3) with respect to , we get
[TABLE]
Now, the first term in the above expression is nonnegative because is IFR, the second term is nonnegative due to () in the hypothesis, the third term is nonnegative because of (), and finally the last term is nonnegative if is increasing in , which is always true. This is because, by (), is convex, which implies that is increasing in , and since is IFR, it is also DMRL, so that is decreasing in . Hence, is IFR.
We now present an application of Theorem 3.1.
Example 3.1
Let follow standard exponential distribution. Take , for all . Clearly, satisfies all the conditions of Lemma 2.1. Again, conditions () and () of Theorem 3.1 are also satisfied. Hence, by Theorem 3.1, is IFR.
The following counterexample shows that condition () of Theorem 3.1 is a sufficient condition but not necessary.
Counterexample 3.1
Let be a random variable having mean residual life , . Take , for all . Then satisfies all the conditions of Lemma 2.1. Again, condition () of Theorem 3.1 is satisfied while condition () is not. Now, for all ,
[TABLE]
which can be shown to be increasing in . Thus, is IFR. Hence, condition () of Theorem 3.1 is a sufficient condition but not necessary.
Remark 3.1
By taking to be a standard exponential distribution, and
[TABLE]
one can show that condition () of Theorem 3.1 is a sufficient condition but not necessary.
The following theorem states the conditions for to be DFR. Here we need to be positive. The proof being similar to that of Theorem 3.1 is omitted.
Theorem 3.2
If the random variable is DFR, then the random variable satisfying (2.2) is DFR provided,
- (i)
* is decreasing in ;* 2. (ii)
* is increasing and concave;*
for all .
Here we present an application of Theorem 3.2.
Example 3.2
Let be a random variable having the failure rate
[TABLE]
Take , for all . Clearly, satisfies all the conditions of Lemma 2.1. One can verify that is decreasing in and also is concave. Thus, by Theorem 3.2, is DFR.
Remark 3.2
In Example 3.2 if we take , for all , then it can be seen that condition () of Theorem 3.2 is a sufficient condition but not necessary, while if in the same example we take
[TABLE]
then it can be shown that condition () of Theorem 3.2 is a sufficient condition but not necessary.
The following theorem shows that the DAMRL model preserves the IFRA (increasing failure rate in average) (resp. DFRA (decreasing failure rate in average)) property under certain conditions on . It is useful to remind that a random variable with failure rate function is said to be IFRA (resp. DFRA) if is increasing (resp. decreasing) in .
Theorem 3.3
If the random variable is IFRA, then the random variable satisfying (2.2) is IFRA provided, for all ,
- (i)
* is increasing in ;* 2. (ii)
* is increasing in .*
: Note, from (2.3), that
[TABLE]
Differentiating with respect to , we get that for all , if
- (a)
, 2. (b)
.
Now, since is IFRA, it can be shown that (a) holds if
[TABLE]
which is true by (). Further, (b) holds by (). Hence, the result follows.
Remark 3.3
Note that Example 3.1 can be considered as an application of Theorem 3.3. Counterexample 3.1 can be considered to show that condition () of Theorem 3.3 is a sufficient condition but not necessary. That condition () of Theorem 3.3 cannot be dropped, can be seen by taking as a standard exponential random variable, and , for all .
The following theorem whose proof is similar to that of Theorem 3.3, shows that the DAMRL model preserves the DFRA property under certain conditions on .
Theorem 3.4
If the random variable is DFRA, then the random variable satisfying (2.2) is DFRA provided, for all ,
- (i)
* is decreasing in ;* 2. (ii)
* is decreasing in . *
Remark 3.4
An application of the above theorem can be considered by taking as standard exponential and as given in (3.5).
Remark 3.5
Considering as in Example 3.2 and , , one can see that condition () of Theorem 3.4 is a sufficient condition but not necessary. That condition () of Theorem 3.4 is a sufficient condition can be seen by considering
[TABLE]
and as in Example 3.2.
The following theorem shows that the DAMRL model preserves the NBU (new better than used) (resp. NWU (new worse than used)) property under certain conditions on . It is useful to remind that a random variable is said to have NBU (resp. NWU) property if , for all .
Theorem 3.5
If the random variable is NBU, then the random variable satisfying (2.2) is NBU, provided, for all ,
- (i)
* is logconvex;* 2. (ii)
* is decreasing in .*
: It can be shown that is NBU if and only if, for all ,
[TABLE]
Since is NBU, it is sufficient to show that, for all ,
[TABLE]
This holds if
[TABLE]
This is true if the hypotheses are true.
Remark 3.6
Example 3.1 can be taken as an application of Theorem 3.5. By taking as standard exponential, and , , one can show that condition () of Theorem 3.5 cannot be dropped. That condition () of Theorem 3.5 is a sufficient condition but not necessary can be seen by taking a random variable having mean residual life , for all , and , for all .
The following theorem whose proof is similar to that of Theorem 3.5 shows that the DAMRL model preserves the NWU property under certain conditions on .
Theorem 3.6
If the random variable is NWU, then the random variable satisfying (2.2) is NWU, provided, for all ,
- (i)
* is logconcave;* 2. (ii)
* is increasing in . *
Remark 3.7
Since a concave function is logconcave, condition () of Theorem 3.6 can be replaced by ‘ is concave’.
Remark 3.8
To present an application of Theorem 3.6, one may take as a standard exponential random variable, and .
The following counterexample shows that condition () of Theorem 3.6 is a sufficient condition but not necessary.
Counterexample 3.2
Let be a random variable with survival function
[TABLE]
It is shown in Nanda, Das and Balakrishnan [1] that is NWU. Take
[TABLE]
Clearly, satisfies all the conditions of Lemma 2.1. Now, we see that, for , is not concave. Again,
[TABLE]
is increasing in . Now, a tedious algebra shows that is NWU. Hence, the condition () of Theorem 3.6 is a sufficient condition but not necessary.
Remark 3.9
Taking to be a random variable having mean residual life , , and , for all , it can be shown that the condition () of Theorem 3.6 is a sufficient condition but not necessary.
The following theorem shows that the model in (2.2) preserves the NBUFR (new better than used in failure rate) property. It is useful to remind that a random variable is said to be NBUFR (resp. NWUFR) if , for all . The proof is omitted.
Theorem 3.7
If the random variable is NBUFR, then the random variable satisfying (2.2) is NBUFR, provided, for all ,
- (i)
; 2. (ii)
.
Remark 3.10
Let be a random variable having mean residual life , , and , . Then one can show that condition () of Theorem 3.7 is a sufficient condition but not necessary.
Remark 3.11
Taking to be a standard exponential random variable and , , it can be shown that condition () of Theorem 3.7 cannot be dropped.
Corollary 3.1
If the random variable is NBUFR, then the random variable satisfying (2.2) is NBUFR provided, for all ,
- (i)
* is decreasing in ;* 2. (ii)
* is increasing in . *
Remark 3.12
Example 3.1 can be considered as an application of Theorem 3.7 and also of Corollary 3.1.
The following theorem shows that the model in (2.2) preserves the NWUFR property.
Theorem 3.8
If the random variable is NWUFR, then the random variable satisfying (2.2) is NWUFR, provided, for all ,
- (i)
; 2. (ii)
.
Example 3.3
As an application of Theorem 3.8, one may take to be a random variable as defined in Example 3.2, and as defined in (3.5).
Counterexample 3.3
Let be a random variable as defined in Example 3.2. Taking , , one can show that condition () of Theorem 3.8 is a sufficient condition but not necessary, where as by taking
[TABLE]
one can show that condition () of Theorem 3.8 cannot be dropped.
Corollary 3.2
If the random variable is NWUFR, then the random variable satisfying (2.2) is NWUFR provided, for all ,
- (i)
* is increasing in ;* 2. (ii)
* is decreasing in . *
Remark 3.13
Example 3.3 can be considered as an application of Corollary 3.2.
The following theorem shows that the model in (2.2) preserves the NBAFR (new better than used in failure rate average) property. It is useful to remind that a random variable is said to be NBAFR (resp. NWAFR) if , for all .
Theorem 3.9
If the random variable is NBAFR, then the random variable satisfying (2.2) is NBAFR, provided, for all ,
- (i)
; 2. (ii)
.
: is NBAFR if, for all ,
[TABLE]
Since is NBAFR, by hypothesis () we have that (3.7) holds if
[TABLE]
which holds by (). Hence the result follows.
Remark 3.14
Let be a random variable having mean residual life , and , . Then one can verify that is NBAFR. Hence, condition () of Theorem 3.9 is a sufficient condition but not necessary. That condition () of Theorem 3.9 cannot be dropped, can be seen by considering as a standard exponential random variable and , .
Corollary 3.3
If the random variable is NBAFR, then the random variable satisfying (2.2) is NBAFR provided, for all ,
- (i)
* is decreasing in ;* 2. (ii)
* is increasing in . *
Remark 3.15
Example 3.1 can be considered as an application of Theorem 3.9 and also of Corollary 3.3.
The following theorem whose proof is similar to that of Theorem 3.9 shows that the model in (2.2) preserves the NWAFR property.
Theorem 3.10
If the random variable is NWAFR, then the random variable satisfying (2.2) is NWAFR, provided, for all ,
- (i)
; 2. (ii)
.
Remark 3.16
Example 3.2, with as given in (3.5), can be taken as an application of Theorem 3.10.
Remark 3.17
Example 3.2 with , , shows that condition () of Theorem 3.10 is a sufficient condition but not necessary. That the condition () of Theorem 3.10 cannot be dropped, can be seen by taking Example 3.2, with as defined in (3.6).
Corollary 3.4
If the random variable is NWAFR, then the random variable satisfying (2.2) is NWAFR provided, for all ,
- (i)
* is increasing in ;* 2. (ii)
* is decreasing in . *
Example 3.4
Let be a random variable as defined in Example 3.2. Clearly is NWAFR. Take as defined in (3.5). In Example 3.3, we see that both the conditions of Theorem 3.10 are satisfied. Hence, by Corollary 3.4, is NWAFR.
4 Conclusion
In this manuscript, we study the properties of the model , which may be considered as a time-dependent additive MRL model. We have given conditions under which can be considered to be an MRL function of some random variable. We have also studied the conditions under which the variable (having MRL function ) belongs to the ageing class C when belongs to the class C. To be specific, let IFR such that satisfies some property . This means that the set of random variables which belong to IFR class satisfying the property , defines a subclass of IFR class, call it C. Then the results studied in this manuscript are the closure properties of C ( IFR). With the help of counterexamples we have shown that the ageing classes like IFR etc. are not closed under the model discussed whereas a subclass of each of these well known classes are closed.
Acknowledgements
This is a part of the PhD thesis of Suchismta Das submitted at IISER Kolkata in 2014. The financial support from NBHM, Department of Atomic Energy, Government of India (Grant no. 2/48(25)/2014/NBHM(R.P.)/R & D II/1393 dated February 3, 2015) is acknowledged by Asok K. Nanda.
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