The statistical properties of spiral- and scroll-wave turbulence in cardiac tissue

TL;DR

This study investigates the statistical properties of spiral- and scroll-wave turbulence in cardiac tissue, revealing similarities and key differences with classical fluid turbulence through extensive direct numerical simulations.

Contribution

First comprehensive analysis applying fluid turbulence statistical methods to cardiac electrical turbulence, highlighting both parallels and unique features.

Findings

Turbulence involves a wide range of spatial scales.

Electrical spectra show approximate power laws over some ranges.

Spiral- and scroll-wave turbulence differ from classical fluid turbulence in important ways.

Abstract

Disorganized electrical activity in the heart leads to sudden cardiac death. To what extent can this electrical turbulence be viewed as classical fluid turbulence,which is an important central problem in modern physics? We investigate,for the first time,via extensive DNSs,the statistical properties of spiral-and scroll-wave turbulence in two- and three-dimensional excitable media by using approaches employed in studies of classical turbulence. We use the Panfilov and the Aliev-Panfilov mathematical models for cardiac tissue. We show that once electrical-wave turbulence has been initiated,there is a forward cascade,in which spirals or scrolls form,interact,and break to yield a turbulent state that is statistically steady and,far away from boundaries,is statistically homogeneous and isotropic. For the transmembrane potential $V$ and the slow recovery variable $g$,which define our models,we define $E_V(k)$ and $E_g(k)$,the electrical-wave analogs of the fluid energy spectrum $E(k)$ in fluid turbulence. We show that $E_V(k)$ and $E_g(k)$ are spread out over several decades in $k$. Thus spiral- and scroll-wave turbulence involves a wide range of spatial scales. $E_V(k)$ and $E_g(k)$ show approximate power laws,in some range of $k$, however,their exponents cannot be determined as accurately as their fluid-turbulence counterparts. The dimensionless ratio $L/\lambda$ is a convenient control parameter like the Reynolds number for fluid turbulence,where $L$ is the linear size of the domain and $\lambda$ the wavelength of a plane wave in the medium. By comparing several other statistical properties for spiral- and scroll-wave turbulence with their fluid-turbulence counterparts,we show that,although spiral- and scroll-wave turbulence have some statistical properties like those of fluid turbulence,overall these types of turbulence are special and differ in important ways from fluid turbulence.