# Can morphological changes of erythrocytes be driven by hemoglobin?

## TL;DR

This paper proposes that thermally induced force-release in hemoglobin can explain the morphological changes observed in erythrocytes at high temperatures.

## Contribution

It introduces a novel explanation linking hemoglobin's thermally induced force-release to erythrocyte morphological changes.

## Key findings

- Erythrocytes change shape at 49°C due to internal forces.
- Hemoglobin's thermally induced force-release correlates with these morphological changes.
- The study provides a new perspective on erythrocyte biomechanics.

## Abstract

At 49 C erythrocytes undergo morphological changes due to an internal force, but the origin of the force that drives changes is not clear. Here we point out that our recent experiments on thermally induced force-release in hemoglobin can provide an explanation for the morphological changes of erythrocytes.