Comments on the arterial spin labelling quantification recommended by the ISMRM perfusion study group and the European consortium for ASL in dementia

TL;DR

This paper critically discusses the recommended arterial spin labeling quantification methods for ASL in dementia, urging for more careful application and validation to ensure accurate perfusion measurement.

Contribution

It highlights the need for cautious implementation of ASL quantification approaches recommended by major groups, emphasizing potential pitfalls and areas for improvement.

Findings

Current ASL quantification methods may have limitations in dementia studies

The paper advocates for more rigorous validation of ASL techniques

It calls for standardized protocols to improve reliability

Abstract

A petition for more careful considerations towards the usage of a quantification approach for ASL which has been recommended by the ISMRM perfusion study group and the European consortium for ASL in dementia.