Distance Metric Learning using Graph Convolutional Networks: Application to Functional Brain Networks
Sofia Ira Ktena, Sarah Parisot, Enzo Ferrante, Martin Rajchl, Matthew, Lee, Ben Glocker, Daniel Rueckert

TL;DR
This paper introduces a novel graph distance metric learning approach using graph convolutional networks and spectral graph theory, specifically applied to functional brain networks to improve disorder classification.
Contribution
It presents a new spectral graph convolutional network-based metric learning method tailored for graph similarity evaluation in connectomics.
Findings
Improves graph similarity assessment for brain networks
Enhances classification accuracy by 11.9% on ABIDE dataset
Demonstrates effectiveness in clinical connectomics applications
Abstract
Evaluating similarity between graphs is of major importance in several computer vision and pattern recognition problems, where graph representations are often used to model objects or interactions between elements. The choice of a distance or similarity metric is, however, not trivial and can be highly dependent on the application at hand. In this work, we propose a novel metric learning method to evaluate distance between graphs that leverages the power of convolutional neural networks, while exploiting concepts from spectral graph theory to allow these operations on irregular graphs. We demonstrate the potential of our method in the field of connectomics, where neuronal pathways or functional connections between brain regions are commonly modelled as graphs. In this problem, the definition of an appropriate graph similarity function is critical to unveil patterns of disruptions…
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Taxonomy
TopicsAdvanced Graph Neural Networks · Bioinformatics and Genomic Networks · Epigenetics and DNA Methylation
Methodsk-Nearest Neighbors
