# Enhanced physicochemical and biological properties of ion-implanted Titanium using Electron Cyclotron Resonance ion sources

## TL;DR

This study demonstrates that ion implantation of calcium and silicon ions onto titanium surfaces via electron cyclotron resonance significantly enhances their physicochemical and biological properties, improving biocompatibility and cell viability.

## Contribution

The paper introduces a novel surface modification method using ECRIS ion sources to improve titanium implant properties with calcium and silicon ions.

## Key findings

- Ion-implanted surfaces showed rougher morphology.
- Ca + Si ion implantation improved electrochemical behavior.
- Enhanced cell viability on ion-implanted surfaces.

## Abstract

The surface properties of metallic implants play an important role in their clinical success. Improving upon the inherent shortcomings of Ti implants, such as poor bioactivity, is imperative for achieving clinical use. In this study, we have developed a Ti implant modified with Ca or dual Ca + Si ions on the surface using an electron cyclotron resonance ion source (ECRIS). The physicochemical and biological properties of ion-implanted Ti surfaces were analyzed using various analytical techniques, such as surface analyses, potentiodynamic polarization and cell culture. Experimental results indicated that a rough morphology was observed on the Ti substrate surface modified by ECRIS plasma ions. The in vitro electrochemical measurement results also indicated that the Ca + Si ion-implanted surface had a more beneficial and desired behavior than the pristine Ti substrate. Compared to the pristine Ti substrate, all ion-implanted samples had a lower hemolysis ratio. MG63 cells cultured on the high Ca and dual Ca + Si ion-implanted surfaces revealed significantly greater cell viability in comparison to the pristine Ti substrate. In conclusion, surface modification by electron cyclotron resonance Ca and Si ion sources could be an effective method for Ti implants.

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Source: https://tomesphere.com/paper/1701.01613