Inferring dissipation from current fluctuations
Todd R. Gingrich, Grant M. Rotskoff, and Jordan M. Horowitz

TL;DR
This paper derives and extends inequalities linking current fluctuations to dissipation in Markov jump and diffusion processes, enabling dissipation inference from coarse-grained observations.
Contribution
It rederives a dissipation-fluctuation inequality, adapts it to diffusion processes, and analyzes how spatial coarse-graining affects dissipation estimation.
Findings
Diffusions saturate the fluctuation-dissipation inequality.
Coarse-grained current fluctuations can bound total dissipation.
Bound tightness depends on detection of large thermodynamic forces.
Abstract
Complex physical dynamics can often be modeled as a Markov jump process between mesoscopic configurations. When jumps between mesoscopic states are mediated by thermodynamic reservoirs, the time-irreversibility of the jump process is a measure of the physical dissipation. We rederive a recently introduced inequality relating the dissipation rate to current fluctuations in jump processes. We then adapt these results to diffusion processes via a limiting procedure, reaffirming that diffusions saturate the inequality. Finally, we study the impact of spatial coarse-graining in a two-dimensional model with driven diffusion. By observing fluctuations in coarse-grained currents, it is possible to infer a lower bound on the total dissipation rate, including the dissipation associated with hidden dynamics. The tightness of this bound depends on how well the spatial coarse-graining detects…
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