The Potsdam MRS Spectrograph - heritage of MUSE and the impact of cross-innovation in the process of technology transfer

TL;DR

This paper introduces the Potsdam MRS Spectrograph, a novel fiber-coupled multi-channel spectrograph inspired by the MUSE design, demonstrating its potential in clinical Raman spectroscopy with high throughput and extended blue performance.

Contribution

It presents a new spectrograph design based on MUSE, optimized for clinical Raman spectroscopy, showcasing innovative optical layout and performance improvements.

Findings

Successful differentiation of complex organic tissue using the spectrograph

High throughput and excellent image quality across a broad wavelength range

Extended blue performance in the spectrograph design

Abstract

After having demonstrated that an IFU, attached to a microscope rather than to a telescope, is capable of differentiating complex organic tissue with spatially resolved Raman spectroscopy, we have launched a clinical validation program that utilizes a novel optimized fiber-coupled multi-channel spectrograph whose layout is based on the modular MUSE spectrograph concept. The new design features a telecentric input and has an extended blue performance, but otherwise maintains the properties of high throughput and excellent image quality over an octave of wavelength coverage with modest spectral resolution. We present the opto-mechanical layout and details of its optical performance.