A Mathematical Model of Cell Reprogramming due to Intermediate Differential Regulator's Regulations

TL;DR

This paper develops a mathematical model of cell reprogramming incorporating delays caused by intermediate regulators, extending previous models to identify critical points of pluripotency.

Contribution

It introduces a novel mathematical model that includes intermediate regulator delays in cell reprogramming, building upon prior models by Ferell Jr. and Mithun Mitra.

Findings

Identified critical points of pluripotent cells

Extended existing models with delay differential equations

Provided insights into regulation dynamics during reprogramming

Abstract

In this paper I have given a mathematical model of Cell reprogramming from a different contexts. Here I considered there is a delay in differential regulator rate equations due to intermediate regulator's regulations. At first I gave some basic mathematical models by Ferell Jr.[2] of reprogramming and after that I gave mathematical model of cell reprogramming by Mithun Mitra[4]. In the last section I contributed a mathematical model of cell reprogramming from intermediate steps regulations and tried to find the critical point of pluripotent cell.