Determinantal sets, singularities and application to optimal control in medical imagery

TL;DR

This paper develops a specialized algorithm for classifying real singularities of polynomial matrices in semi-algebraic sets, enabling improved control in medical imaging applications like MRI contrast enhancement.

Contribution

A novel algorithm exploiting determinantal structure for efficient real root classification of polynomial matrix singularities in control problems.

Findings

Algorithm speeds up computations by a factor of 100.

Successfully applied to MRI contrast optimization.

Partitioned medical imaging problem into three classes.

Abstract

Control theory has recently been involved in the field of nuclear magnetic resonance imagery. The goal is to control the magnetic field optimally in order to improve the contrast between two biological matters on the pictures. Geometric optimal control leads us here to analyze mero-morphic vector fields depending upon physical parameters , and having their singularities defined by a deter-minantal variety. The involved matrix has polynomial entries with respect to both the state variables and the parameters. Taking into account the physical constraints of the problem, one needs to classify, with respect to the parameters, the number of real singularities lying in some prescribed semi-algebraic set. We develop a dedicated algorithm for real root classification of the singularities of the rank defects of a polynomial matrix, cut with a given semi-algebraic set. The algorithm works under some genericity assumptions which are easy to check. These assumptions are not so restrictive and are satisfied in the aforementioned application. As more general strategies for real root classification do, our algorithm needs to compute the critical loci of some maps, intersections with the boundary of the semi-algebraic domain, etc. In order to compute these objects, the determinantal structure is exploited through a stratifi-cation by the rank of the polynomial matrix. This speeds up the computations by a factor 100. Furthermore, our implementation is able to solve the application in medical imagery, which was out of reach of more general algorithms for real root classification. For instance, computational results show that the contrast problem where one of the matters is water is partitioned into three distinct classes.