DNA to DNA transcription might exist in eukaryotic cells
Gao-De Li
TL;DR
This paper proposes the possibility of DNA to DNA transcription in eukaryotic cells, based on experimental evidence from Plasmodium falciparum, which could reveal new functions of noncoding DNA.
Contribution
It introduces the novel concept of DNA to DNA transcription in eukaryotes, supported by experimental findings, expanding current understanding of genetic transcription processes.
Findings
Evidence of DNA to DNA transcription in Plasmodium falciparum
Implications for noncoding DNA functions in eukaryotic genomes
Potential new mechanisms of genetic regulation
Abstract
Till now, in biological sciences, the term, transcription, mainly refers to DNA to RNA transcription. But our recently published experimental findings obtained from Plasmodium falciparum strongly suggest the existence of DNA to DNA transcription in the genome of eukaryotic cells, which could shed some light on the functions of certain noncoding DNA in the human and other eukaryotic genomes.
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Taxonomy
TopicsRNA and protein synthesis mechanisms · CRISPR and Genetic Engineering · RNA modifications and cancer