Single-shot optical imaging through scattering medium using digital in-line holography

TL;DR

This paper introduces a simple, non-invasive digital in-line holography method that enables single-shot complex amplitude imaging through scattering media by using speckle autocorrelation, with potential biomedical applications.

Contribution

The proposed approach combines digital in-line holography with speckle autocorrelation to achieve single-shot imaging through scattering layers without complex transmission matrix measurements.

Findings

Successfully retrieves complex amplitude images behind scattering media

Uses simple optical setup and experimental procedure

Applicable to biomedical and deep tissue imaging

Abstract

Non-invasive and single-shot holographic imaging through complex media is technically challenging due to random light scattering which significantly scrambles optical information. Recently, several methods have been presented to address this issue. However, they require complicated measurements of optical transmission matrices, or existing techniques do only retrieve intensity information. Here we propose and experimentally demonstrate a holographic approach for single-shot imaging through a scattering layer based on digital in-line holography in combination with the autocorrelation of the speckle intensity. Using a simple optical configuration and experimental procedure, the proposed method enables to retrieve the complex amplitude image of an object located at arbitrary planes behind scattering media. The technique has potential applications in biomedical imaging, deep tissue microscopy, and 3D imaging through turbid media.