The Graph of Our Mind
Bal\'azs Szalkai, B\'alint Varga, Vince Grolmusz

TL;DR
This study analyzes large-scale brain graphs derived from diffusion MRI data of 426 subjects, revealing significant sex-based differences in graph-theoretic properties, and provides the data publicly for further research.
Contribution
It significantly expands previous work by analyzing more subjects and makes the braingraph data publicly available for community validation and further studies.
Findings
Female braingraphs are better expanders.
Female braingraphs have more edges.
Significant sex-based differences in graph parameters.
Abstract
Graph theory in the last two decades penetrated sociology, molecular biology, genetics, chemistry, computer engineering, and numerous other fields of science. One of the more recent areas of its applications is the study of the connections of the human brain. By the development of diffusion magnetic resonance imaging (diffusion MRI), it is possible today to map the connections between the 1-1.5 cm regions of the gray matter of the human brain. These connections can be viewed as a graph: the vertices are the anatomically identified regions of the gray matter, and two vertices are connected by an edge if the diffusion MRI-based workflow finds neuronal fiber tracts between these areas. This way we can compute 1015-vertex graphs with tens of thousands of edges. In a previous work, we have analyzed the male and female braingraphs graph-theoretically, and we have found statistically…
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